And yes, you can have your feeding window whenever it feels right.
... I wonder if that's the same certainty that led to thalidomide.
Apologies for late reply Smet. Been learning/building a new website for business rebrand and had fuck-all time to spare. Little time to catch up on real life activities, let alone IGx.
Endotoxins, insulin response etc... Yeah, OK. No disagreement at all.
However as you say, the mechanisms are cloudy. Which always raises the question if these things aren't just artifact results gained from studying unhealthy people. E.g. leaky gut effect on endotoxin, and what is 'normal' anyway etc..?
It always comes to back to us actually not knowing what the baseline physiology of a 'healthy human' is. It's hard to deduct the complex interplay by studying humans in captivity. And we'll probably never know now, due to DDT, radiation, etc, etc. We can only try to shift factors in our favour. Due to non linearity, we'll also never fully know the 'percentage' benefit we might gain.
The future may hold some interesting findings regarding timing of sleep/feeding etc. Its long term effect on the ability for the human complex self-organising system to maintain a coherence that allows the individual to achieve somewhere close to their potential for 'health'.
Anyhow this popped up this morning whilst looking for something else...
"The Biological Clock: A Pivotal Hub in Non-alcoholic Fatty Liver Disease Pathogenesis"
Which led me to this, which isn't new, but worth noting...
"A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells"
(Warning: Stand on a chair whilst reading the first one. There's some rodent references).