Wu Flu

Schlegel · Post by **Schlegel** » Thu Aug 13, 2020 7:21 pm

Bennyonesix1 wrote: ↑Thu Aug 13, 2020 4:10 pm More possible good news. Tcell immunity could be measured without massive cost. We'd know if the 80% number is correct and who doesn't need a vaccine.

"sandeep chakraborty
@sanchak74
This is how one measures Tcells response - different from Bcells antibodies (which varies) - by measuring (a constant) protein IFN-gamma

Pre-existing Tcells exposed to Cov2 (or Cov2-like) will secrete IFN-gamma when it meets a viral antigen.

Should be reasonably easy and cheap"

https://www.technologynetworks.com/diag ... ssion=true

Would work, problem it's more expensive to do than an antibody ELISA, and is a multiday process using fresh blood with live cells and cell culturing in an incubator instead just a one day procedure that can be done benchtop. A random survey done this way would be very valuable as a predictor, though. Could get pretty good throughput as an ELISpot assay and the sensitivity is excellent.

Sangoma · Post by **Sangoma** » Thu Aug 13, 2020 11:25 pm

There are two simple proven ways to improve immunity: cold exposure and saunas. Few things are simpler than a cold shower. Fasting is another way, though less researched and its effects are more complex. At the very least not overeating is beneficial.

Fat Cat · Post by **Fat Cat** » Thu Aug 13, 2020 11:27 pm

I see people smoking all around me and then they have the audacity to tell me to wear a mask. Off the top of my head I can think of four or five more serious public health issues: smoking, obesity, type 2 diabetes, alcoholism, drug addiction, automobiles, etc.

Sangoma · Post by **Sangoma** » Thu Aug 13, 2020 11:30 pm

Years ago I saw a photo from a newspaper: heavily pregnant woman is standing outside of her house with the lit cigarette in her hand, looking at the group of road workers with some machinery some distance in front of her. The headline says: "Maria so-and-so is concerned the noise can harm her baby". Talk about misplaced perspective.

Fat Cat · Post by **Fat Cat** » Fri Aug 14, 2020 12:12 am

I work in a typical high rise office building. No smoking inside, but out front people gather, dutifully remove their masks, and light the fuck up. It blows my mind.

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 12:47 am

Sangoma wrote: ↑Thu Aug 13, 2020 11:25 pm There are two simple proven ways to improve immunity: cold exposure and saunas. Few things are simpler than a cold shower. Fasting is another way, though less researched and its effects are more complex. At the very least not overeating is beneficial.

Yeah ppl need to quit being fat.

And ensuring vitD is at acceptable levels is important as well.

But honestly, not being old enough to be in a nursing home in NY or NJ or PA or CT or DE is the an almost certain proof against dying.

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 1:01 am

Turdacious wrote: ↑Thu Aug 13, 2020 4:40 pm
Bennyonesix1 wrote: ↑Thu Aug 13, 2020 4:32 pm
Turdacious wrote: ↑Thu Aug 13, 2020 4:17 pm
Bennyonesix1 wrote: ↑Thu Aug 13, 2020 3:19 pm I came to a realization this morning.

We're not getting through this until Big Pharma gets paid for making a vaccine.

Their regulatory capture of the US and world health system means they can make this happen.

I wish they'd just take money to go away like the mafia and leave us alone but for some reason they've decided on a vaccine.

The smartest thing for politicians to do is figure out a way to get the money to them while limiting the amount of vaccinations and also putting in stops to prevent their doing this again.
Big Pharma is probably right on this one. There’s a lot of risk here (many companies will try, few will succeed), the margins on vaccines are low, It won’t be a long term profit generator, and governments tend not to keep their word to companies when it comes to public health.

https://www.spiegel.de/international/wo ... ssion=true
That kind of makes my point.

Glad you've admitted I'm correct.

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 1:18 am

Paper has herd immunity at 40%. This is the highest I've seen. As Professor Balloux points out HIT strongly dependent on the nature of the network and isn't a constant.

https://science.sciencemag.org/content/369/6505/846

Turdacious · Post by **Turdacious** » Fri Aug 14, 2020 1:26 am

Bennyonesix1 wrote: ↑Fri Aug 14, 2020 1:18 am Paper has herd immunity at 40%. This is the highest I've seen. As Professor Balloux points out HIT strongly dependent on the nature of the network and isn't a constant.

https://science.sciencemag.org/content/369/6505/846

He's using Kellyanne Conway's definition of herd immunity of coarse.

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 1:37 am

Turdacious wrote: ↑Fri Aug 14, 2020 1:26 am
Bennyonesix1 wrote: ↑Fri Aug 14, 2020 1:18 am Paper has herd immunity at 40%. This is the highest I've seen. As Professor Balloux points out HIT strongly dependent on the nature of the network and isn't a constant.

https://science.sciencemag.org/content/369/6505/846
He's using Kellyanne Conway's definition of herd immunity of coarse.

NO ONE CARES

STOP BEING SO DULL FOR ONE POAST

Fat Cat · Post by **Fat Cat** » Fri Aug 14, 2020 1:41 am

He can't Benny. He simply cannot.

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 1:45 am

Nice work neo-lib NGO Big Pharma lockdown fans.

You stopped a few winners in your BS "meritocracy" from getting the flu and fucked the world. Nice work assholes.

https://www.nature.com/articles/d41586- ... 6-43376169

Turdacious · Post by **Turdacious** » Fri Aug 14, 2020 4:31 am

Fat Cat wrote: ↑Fri Aug 14, 2020 1:41 am He can't Benny. He simply cannot.

It’s for his own good. He’s a few years away from being an HOA president. Not a good path

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 2:26 pm

God I hate HOAs. The single largest unexposed source of graft in the US.

nafod · Post by **nafod** » Fri Aug 14, 2020 5:50 pm

DrDonkeyLove... wrote: ↑Wed Aug 12, 2020 11:48 am I heard about a very simple and cheap test yesterday. I believe it's referred to as a "spit test". It seems like it works similarly to a pregnancy test. Deposit some saliva on a strip of some kind and you get an indicator that says you have COVID to the point where you're infectious or not.

There are apparently CDC reporting requirements that complicate things but imagine a world where we could test ourselves every time we had the sniffles or wanted to be in a group. Seems like it would help open the world a lot without a excess complexity. I hope it's true.

Good article on it, and other testing, here.

https://www.theatlantic.com/health/arch ... ay/615217/

Yes it's not super accurate, but you could test yourself multiple times per day every day. Goal is to identify people who are contagious rather than people who are (or were) infected. In that, they can be superior to the current tests.

Sangoma, for you...

We must out-volume the virus, and what will matter is not the strength of any one individual ship, but the strength of the system it is part of. When the FDA regulates tests, though, it looks at the sensitivity and specificity of a single test—how well the test identifies illness in an individual—not at how the test is part of a testing regimen meant to protect society. For this reason, Mina proposes that the FDA make room for the CDC or the NIH to oversee the use of contagiousness tests.

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 6:00 pm

You're delusional and utterly consumed by neuroses if you think ppl need to test themselves multiple times a day with a crap test because of the significance of the threat posed by covid.

You're pot committed with a shit hand.

Bayes is midwit catnip but please nigga update some priors.

Fat Cat · Post by **Fat Cat** » Fri Aug 14, 2020 6:05 pm

Bennyonesix1 wrote: ↑Fri Aug 14, 2020 6:00 pm You're delusional and utterly consumed by neuroses if you think ppl need to test themselves multiple times a day

lololol that's pretty much exactly what I thought when I read that. I think I'd rather just take my chances, thanks.

Three clappies for you!

nafod · Post by **nafod** » Fri Aug 14, 2020 6:09 pm

Bennyonesix1 wrote: ↑Fri Aug 14, 2020 6:00 pm You're delusional and utterly consumed by neuroses if you think ppl need to test themselves multiple times a day with a crap test because of the significance of the threat posed by covid.

You're pot committed with a shit hand.

Bayes is midwit catnip but please nigga update some priors.

If we did it, we wouldn't be half-assed dicking around with this virus for another 12-18 months, killing off lots of old people and bouncing back and forth between wide open and locked down. It would be gone.

But we (and I mean people like you) are too stupid for something like that.

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 6:11 pm

nafod wrote: ↑Fri Aug 14, 2020 6:09 pm
Bennyonesix1 wrote: ↑Fri Aug 14, 2020 6:00 pm You're delusional and utterly consumed by neuroses if you think ppl need to test themselves multiple times a day with a crap test because of the significance of the threat posed by covid.

You're pot committed with a shit hand.

Bayes is midwit catnip but please nigga update some priors.
If we did it, we wouldn't be half-assed dicking around with this virus for another 12-18 months, killing off lots of old people and bouncing back and forth between wide open and locked down. It would be gone.

Get a hold of yourself woman.

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 6:53 pm

Two great tweets about how data reporting can influence projections. Here, how counting deaths by date of death results in once projection and how counting via date of report results in another. Obvious when one thinks about it. But really well shown here.

First post

Second post

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 7:32 pm

Could be a huge development. Increased pool of people with resistance to covid.

"Importantly, SARS-CoV-2-specific T cells were detectable in antibody-seronegative exposed family members and convalescent individuals with a history of asymptomatic and mild COVID-19. Our collective dataset shows that SARS-CoV-2 elicits robust, broad and highly functional memory T cell responses, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19."

https://www.cell.com/cell/fulltext/S009 ... -4?rss=yes

Edit

41% of sero-negatives had the Tcells.

Fat Cat · Post by **Fat Cat** » Fri Aug 14, 2020 7:35 pm

Why can't we just let the fat people die?

Bennyonesix1 · Post by **Bennyonesix1** » Fri Aug 14, 2020 7:40 pm

Haven't we all died already?

nafod · Post by **nafod** » Fri Aug 14, 2020 7:42 pm

Fat Cat wrote: ↑Fri Aug 14, 2020 7:35 pm Why can't we just let the fat people die?

My BIL still lives, so its not working

Fat Cat · Post by **Fat Cat** » Fri Aug 14, 2020 7:58 pm

Bennyonesix1 wrote: ↑Fri Aug 14, 2020 7:40 pm Haven't we all died already?

Only on the inside! $\:D/$

IGX

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